#
from tkinter import *
rootWin = Tk()

entry = Entry(rootWin)
entry.grid(row=0,column=0,columnspan=2,pady=50,padx=10)

button1 = Button(rootWin, text="#1")
button2 = Button(rootWin, text="#2")

button1.grid(row=1,column=0, sticky=E)
button2.grid(row=1,column=1,sticky=NSEW)

#VS

rootWin.title("This is the title!!")

rootWin.mainloop()